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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

有些行业将会比其他的复苏得快一些。像建筑,制造这样的行业可以马上就开始招聘了。然而,零售,旅游,医疗这些依靠客户消费的行业则可能是复苏得最慢的。
NPLs rose from 1.25 per cent of total loans to 1.67 per cent by the end of 2015, amounting to Rmb1.27tn held by commercial banks.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

哈佛大学发言人瑞秋?戴恩拒绝对该新闻发表评论。她在邮件中写道:“我们对于个别申请人的录取情况不予置评”。
埃玛·莫拉诺(Emma Morano)

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

And the best gig for 2015? That would be an actuary, the people who specialize in financial risk.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

1. Asana.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
From the themed collection: 从圆住房梦到房住不炒
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

《老友记》是成长在90年代的小伙伴们心中标志性的存在,因为它的主题:友谊、大城市生存的不易,发现自我、寻求独立,与年轻人息息相关,如今亦是如此。
n. 休息寓所,撤退,隐居
The most staggering scene is, of course, that in which the alien picks up a young man with the facial condition neurofibromatosis, played by Adam Pearson. Glazer brings to this scene an utter fearlessness and unsentimentality, perhaps a variation on a theme from David Lynch’s The Elephant Man. The alien does not essentially distinguish between his looks and those of her other victims, but her encounter with him – an encounter of two aliens? – triggers a crisis in which she becomes the prey rather than the hunter.
雷文斯克罗夫特最终不再从事教学工作,他创办了Enabling Enterprise,这是一家寻求减轻学校和企业脱节现象的机构,它让学生走出教室,从事实践项目并实地探访包括瑞银(UBS)和富而德律所(Freshfields)在内的企业。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

据"可信证据"流行小天王Justin Bieber当爸爸了!
Admittedly, choosing the most clichéd gender colors can seem a bit simplistic, but Pantone has a broad constituency to manage; this is not about the cutting edge, but the big middle.
n. 港口,避难所,安息所 v. 安置 ... 于港中,
而相对来说,普遍推出的新限购政策,并未让其他许多最近几个月表现突出的城市受到影响,房价同比依然大幅上涨。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

根据周一发布的年度调查报告,如今实现澳大利亚梦的成本急剧上升,悉尼和墨尔本超过大多数欧美城市,跻身世界最贵城市前五名。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

You’re a busy person. At times, it all can feel overwhelming. Asana is a cloud-based project management software that helps you keep it together. (Trust me, I’ve tried them all.) Flexibility is built into Asana’s architecture. Each “task”, or “subtask”, can be associated with a larger “project” and “department.” In addition, you can even assign recurring tasks to yourself or team, which makes life so much easier. Stop trying to remember all the things you’re supposed to do and let Asana structure your life.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

单词yacht 联想记忆:
“温总理的讲话重点提到了经济和社会发展。中国政府为实现建设繁荣社会这一目标付出了巨大的努力。”Irene Giner-Reichl, Austrian ambassador

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

沪深300指数(CSI 300)包含了沪深两市交易的300支主要A股,其于2016年交易首日下跌7%,根据新推行的市场熔断机制,意味着当日股市交易已结束。
比特币发展势头强劲的另一个指标是,接受比特币的主流企业数量增加。2014年,微软、贝宝、戴尔以及Dish Network等企业宣布,自身一系列产品接受比特币付款。此前已有塔吉特(该公司接受能以比特币购买的Gyft)、Overstock.com以及WordPress等公司接受比特币。就连《财富》出版商——时代公司,也开始接受比特币杂志订阅。去年,雅虎还将比特币加入其雅虎财经跟踪网站,令比特币更显正统。谷歌财经也很快依样画葫芦。雅虎发言人向CoinDesk网站表示:“接受比特币越来越普遍,我们觉得这与我们行业、我们用户切身相关。”假如雅虎很快更大力押宝比特币——不论是收购比特币新创企业,还是宣布其他动作——都别太惊讶,因为雅虎首席执行官玛丽莎o梅耶尔正努力使这家止步不前的搜索巨头变得更时髦。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

《老友记》播出之时,正值来自小城镇的美国年轻人向大城市转移的时代,而初到大城市的年轻人既不够成熟,也缺乏独自生存的能力。在此之前,情景喜剧都以展现家庭百态为主,父母是剧中的主要人物。但是,当年轻人独自在大城市生活时,他们不得不依靠彼此,一起度过迷茫的青春。
The most staggering scene is, of course, that in which the alien picks up a young man with the facial condition neurofibromatosis, played by Adam Pearson. Glazer brings to this scene an utter fearlessness and unsentimentality, perhaps a variation on a theme from David Lynch’s The Elephant Man. The alien does not essentially distinguish between his looks and those of her other victims, but her encounter with him – an encounter of two aliens? – triggers a crisis in which she becomes the prey rather than the hunter.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

捷克模特皮德拉·尼姆科娃选择了一件白色连衣裙,这件裙子的特色就是深V领口以及长及大腿的裙摆开叉。这位极有魅力的金发女郎极力突出自己轻盈的美腿,确保自己走上红毯的时候可以吸引所有人的目光。
“As the economy enters the ‘new normal’, the industry sector faces increased downward pressures, unreasonable structures and weak innovation capability,” Mao Weiming, vice-minister at the Ministry of Industry and Information Technology, said at a press conference.
《蓝色茉莉》(Blue Jasmine):按年代顺序排列,本片属于导演伍迪?艾伦(Woody Allen)自我更新晚期的作品。不过,从艺术角度看,该片算得上是伍迪?艾伦作品中最优秀的喜剧之一。该片的卖点是凯特?布兰切特(Cate Blanchett)的出彩演绎,曾在《欲望号街车》中出演布兰奇?杜布瓦(Blanche DuBois)的凯特?布兰切特这一次出演女主角茉莉,离婚后精神状态有些癫狂。亚历克?鲍德温(Alec Baldwin)在剧中扮演茉莉的丈夫,是一个类似于马多夫(Bernie Madoff)的行骗者。其他人物方面,在经历了欺骗和失望后,莎莉?霍金斯(Sally Hawkins)、安德鲁?戴斯?克莱(Andrew Dice Clay)鲍比?坎纳瓦尔(Bobby Cannavale)以及路易?C.K(Louis C.K.)等人扮演的角色最终都找到了自己的方向。
However, 2016 saw the rise of Chinese mobile phone-makers. Huawei shipments grew 30.2 percent year on year to 139.3 million units, and the company retained its No. 3 position globally.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

This can involve everything from not responding to e-mails to not being aware of how you come across in an e-mail. If you have a bad habit of taking too long to check or respond to e-mails, you could miss important meetings or deadlines, cause delays or confusion, or come off as unprofessional.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 新型建筑材料未来市场潜力无限
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

8. 赤脚能够提高记忆力
5. bedazzled / a . 眼花缭乱的。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

1. Asana.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

associate

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Take solid and effective steps to cut overcapacity
社交网络内容将出现在谷歌搜索结果页面
“We do things for other reasons than a profit motive, we do things because they are right and just,” Mr Cook growled. Whether in human rights, renewable energy or accessibility for people with special needs, “I don’t think about the bloody ROI,” Mr Cook said, in the same stern, uncompromising tone that Apple employees hope they never have to hear. “Just to be very straightforward with you, if that’s a hard line for you?.?.?.?then you should get out of the stock.”
在周二发布的一份研究报告中,行业组织国际金融协会(Institute of International Finance)经济学家罗宾?克普克(Robin Koepke)表示,投资者、新兴市场政策制定者以及美联储自身都忽视了美国利率在引发新兴国家汇率、银行及债务危机方面的作用。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

201110/156989.shtmlThe Victoria's Secret Fashion Show just taped, and this year's was one of the most elaborate ever.
目前,达洛伊西奥80%的工作围绕着Summly的重构和改良展开,而另外20%的工作精力则用来思考今后的挑战方向。他预测,未来将会有一款如同Summly精炼文字一样可以精炼视频的软件。他设想了许多运用科技来帮助人们学习知识的方法,并希望在旧有教育模式瓦解的同时帮助人们更好地实现自主学习。
On Saturday night they sang Stars from Les Miserables, the song performed the character Javert in the long-running musical.
credit
瑞士、瑞典、英国再次占据榜单前三名。全球创新指数25强经济体中,有15个来自欧洲。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

福布斯表示,如果不扣除管理费和税费,在2015年6月1日到2016年6月1日期间,全球收入最高的10位女星共入账2.05亿美元。
v. 施压

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

研究显示,美国已经取代印度成为反倾销和其他贸易保护案件的最大发起国,而中国及其钢铁行业正是美国的最大目标。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
From the themed collection: 供应 建立多级体系
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

There were more than 8m Chinese tourist arrivals in the country last year — up 36 per cent year-on-year, said Mr Wang. The numbers had continued to increase even after Seoul announced the deployment of Thaad, he added.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

事实是,韩力不是第一个发明电子烟的人。早在1963年,赫尔伯特·吉尔伯特就制造出了世界上第一个可以用来吸入香烟味儿空气的装置。他最初的发明装置,不用燃烧,也不含尼古丁。他后来设计出了一个用电池去加热的模型,他也用了不同味道的水去制造蒸气。他把他的电子烟模型展示给不同的化工、制药以及烟草公司,但是他们都没有理会他的模型。
adj. 暴露的,无掩蔽的,暴露于风雨中的 v. 暴露,
The third gunman, Amedy Coulibaly, who stormed a kosher supermarket on Friday,never left for such training, said Valls.
The image of a smooth-talking, chain-smoking and sexist James Bond may be a thing of the past as the latest 007 novel gives him a politically-correct makeover.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

达奇斯说:星巴克在社交方面总是排名前列,2012年也不例外。公司通过社交在2012年赢得了1900万新的粉丝,它针对用户在家和出门的产品也成为用户津津乐道的谈资。
Create a mood board for inspiration, including quotes and pictures that will invigorate your creative juices. You might even want to change it up once and a while if you have a major project due or need fresh ideas. Art or wall décor can also add a creative touch to your workspace. We recommend the 3 in 1 Board, $19.95, at CB2.com (pictured above).
[kri'eitiv]
The demagogue’s campaign leads naturally to despotism — the tyranny of the majority that is a mask on the tyranny of one.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

要向依法依规的市场主体发出“前行、前行、再前行”的信号;向依靠劳动创业创新者亮起“可以、可以、再可以”的绿灯;对那些违法违规不良行为,就要及时亮出黄牌,甚至出红牌罚他下场。
The residents of the Hankou Binjiang estate had been moved out weeks before.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

When asked if the central bank would do more, Dario Perkins, chief European economist at Lombard Street Research, said: “I don’t think so, unless something goes wrong in the wider global economy.”
Final predictions: Weak economic growth will continue into 2010. By spring, the Obama White House will be forced to the political center and U.S. businesses will finally believe in a modest recovery.
伦敦阿格纽艺术品交易所(Agnew’s)的主管安东尼·克赖顿-斯图尔特(Anthony Crichton-Stuart)说:“如果没有意识到我们处在非常危急的关头,那就太天真了。人们的偏好出现了重大转变。但是如果拍卖会上出现一幅18世纪前绘画大师的佳作,而且价位合理,人们还是会感到兴奋。”
worthwhile
This was never more powerful than when he talked publicly for the first time about his sexuality.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

中国富豪王健林旗下拥有AMC Theaters等产业,在今年的榜单上进入了前20位。
第三,麦克德莫特可以作为一道保险,以防如果今年夏天安德烈-罗伯森选择自由离开时雷霆无人可用。
10. Are YOU Re-Energized?

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

作为每年都会有超过100万人参加的国家级考试,研究生入学考试对于学生的学习生涯是非常重要的,而作弊事件也一而再再而三被曝光。
提供公务员考试培训的教育机构中公网校的数据显示,报名首日共有31220人通过审核,超过去年同期的2.5万人。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

会建立起稳定、流动性较强的比特币期货市场吗?
How the longer maternity leave policy is implemented is up to local governments to decide. Specific and legally-binding measures should be worked out at the national level to ensure the policy is carried out and properly enforced to ensure that women are not discriminated against by employers obsessed with minimizing their labor costs.
1. Will China's housing prices peak in 2010?

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

‘Veep’ “House of Cards,” the Netflix phenomenon, showed its weaknesses this year, but HBO’s “Veep,” the other most cynical show about Washington, got stronger in its third season. The scene in a restroom in which Selina (Julia Louis-Dreyfus) and her assistant, Gary (Tony Hale) discover that she is going to become president and dissolve into uncontrollable laughter was one of the great comic moments of 2014.
Of course, these same new forces may also trigger a backlash and a reversion to old command-and-control ways of leading. The politicians who dominate the world stage are, depressingly, mostly cut from the old cloth, and the leadership challenges they face, from Brexit to North Korea, are particularly complex.
继8月中旬贬值后,人民币在9月和10月有所上涨,但在11月再度走低,昨日人民币汇率收跌至三个月最疲弱水平,为1美元兑6.4082元人民币。“中国周边很多国家自10月份起经历了一些资本外流,中国也未能幸免,”深圳招商证券(China Merchants Securities)经济学家谢亚轩表示。“美元走强势必在一定程度上引发转投美元资产的行为。”

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: 家居企业整合资源抱团作战成出路
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

众所周知中国一直在雄心勃勃地推进航天商业化,最近中国取得的进展正在将这一梦想转为现实。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

Manohla Dargis

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

New Year should be a time of banked-up fines, the scent of flowers and wine, good talk, good memories and loyalties renewed. But if all else is lacking - love will do.
WhatsApp had been particularly ad-averse before its sale to Facebook. CEO Jan Koum kept a note from co-founder Brian Acton taped to his desk to remind him of the company’s core values. It read: “No Ads! No Games! No Gimmicks!”

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

4. 詹妮弗-安妮斯顿 2100万美元
“As long as overall markets remain relatively constructive and transactions continue to be executed well, we continue to expect healthy volumes over the rest of the year,” said David Ludwig, head of Americas equity capital markets at Goldman Sachs.
Users say the voice messages are transferred quickly enough to have a conversation on the platform. But different from free voice applications such as Microsoft Corp.'s Skype, it also offers the flexibility of answering messages at a later time. 'I can decide when to reply, or not to,' said Beijing WeChat user Robin Wang.
据报道显示,一些贷款机构一直在利用借贷宝向女大学生提供高息贷款,条件是贷款人必须提供持有身份证拍摄的裸照作为抵押。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

在西方国家更新、更广泛的国民身份认同里,白人们也有自己的一席之地。但是除非他们接受这一点,“白”的危机仍会持续存在下去。
“We had to make Steve look like a blue-blooded man of great family wealth,” Mr. Corso said. “There’s a specific look, a definite visual that goes along with that.”

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

她表示:“美国宪法第一修正案中对于言论自由的保护仅针对公共实体的违法情况,而哈佛是所私立大学,所以第一修正案根本不适用。”
北京某投资公司总经理汪杰表示,金融和地产业高管较高的薪酬反映出我国发展不平衡的问题。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

TOGETHERNESS (HBO, Jan. 11) HBO’s Sunday night comedy block already covers early-20-something New York women (“Girls,” beginning its fourth season the same night) and late-20-something San Francisco gay men (“Looking,” beginning its second). Now it adds 30-something Los Angeles straight people in this sometimes bleakly comic half-hour from Jay and Mark Duplass, the brothers behind quirky films like “The Puffy Chair” and “Baghead.” Mark Duplass and Melanie Lynskey play a married couple sharing a house with his best friend (Steve Zissis) and her sister (Amanda Peet).

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
From the themed collection: 从圆住房梦到房住不炒
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

雅虎首席执行官玛丽莎梅耶尔
Technology and telecoms are on the up as are some fast food companies, including Starbucks, which BrandZ puts in this category, and McDonald's, whose brand value is risen by nine per cent even though its ranking is unchanged.
But I know your generation, unlike any other generation in the past, is most eager to look at life differently. So as you leave school, I offer you a list of some obvious-yet-vastly-ignored truths that may help you look at life a little differently than just a series of paychecks:
But Choupette isn't only a kept kitty, for she made more than £2.3million in one year alone after appearing in just two ad campaigns — one for Japenese beauty product Shu Uemura, and for German car company Vauxhall.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

Please accept my sincere wishes for the New Year. I hope you will continue to enjoy good health.
由美国演员Jared Leto领衔的“火星三十秒”拿到了最佳另类音乐奖,同时还有Lana Del Rey,Lorde,The XX和Imanine Dragons等人提名。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

On this season I have but one thing to say: I love you.值此佳节,我只有一句话要告诉你:我爱你
The scientists’ analysis comes only a month after nearly 200 governments struck a new climate agreement in Paris that aims to stop global temperatures from rising more than 2C from pre-industrial levels, and ideally limit warming to 1.5C.
Crown Prince Mohammed bin Salman said the majority of those being detained had agreed to pay back some of the money they had gained illegally in exchange for their freedom.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

在所有这些影片中,斯文顿用的是同一个牙齿设计专家——伦敦Fangs F/X公司的克里斯·莱昂斯(Chris Lyons)。他在工作中设计了各种牙齿,包括为坎耶·韦斯特(Kanye West)一个音乐录影带中的一只杜宾犬设计了金色尖牙。
adolescent
“The Man Who Knew is an impressive work of scholarship,” Lionel Barber, editor of the FT and chair of the book award judges, said. “It’s a masterpiece of political economy and, above all, it’s a great and enjoyable read.”

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

3. Dan Weiss “Fourteen” (Pi Recordings) There’s so much in “Fourteen,” the album-length composition by the drummer Dan Weiss: meticulous chamber maneuvers; avant-garde yowling; wordless vocals of new-music and northern Indian pedigree. More impressive than the expansive frame of reference is the fact that Mr. Weiss, marshaling about a dozen of his peers, spins it all into a flowing fabric.
一些智能的床会让你有更好的睡眠质量和睡眠姿势,但也会让你变成一个检查配偶是否出轨的私家侦探。除了检测这个床垫是否舒适,它会在有其他人占用你的床的时候提醒你。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

fare
和你共事的多数同事你都不喜欢
In this post, we’ll take a look at 16 software applications that I use almost every day — and discuss why you should too.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

Look up "side-splitting humor" in the dictionary and you should probably come across the trailer for Girls Trip, which is the funniest movie of 2017, no contest.
丽萨斯通

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

the Dutch lender that is a leading financier to farmers and agribusinesses around the world.
in进入,stitute站,建立-站进去;进入建立的状态-创立
We will continue to work to see that government functions are fully carried out in accordance with law.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

单词supply 联想记忆:

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Since the establishment of Avic 1 and Avic 2 in 1999, which really marked the beginning of China’s push into the commercial aerospace market, there has been no doubt about China’s intent and the direction it wants its industry to take. But the pace at which it would achieve this ambition was less uncertain. Almost 20 years on, things have become much more clear, and there is now little doubt that China is well on its way to succeeding where several other countries have failed in becoming a full-fledged player in the large commercial aircraft manufacturing sector, with the potential to disrupt the long-standing duopoly of Airbus and Boeing.
据《每日经济新闻》网报道,经过一项最新调查显示,经济和金融类院校毕业生最有'钱'途。国内5大财经类高校毕业生的平均月薪在1万元以上。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

银行根本无力赶上这样的薪酬水平。例如,受交易结构性变化和旨在约束冒险行为的新规打击,自2009年以来高盛(Goldman Sachs)的净收入减少了约三分之一。该行试图让薪酬比保持稳定,这意味着发放给典型员工的总薪酬减少。
TextPride changed its name to Swyft Media and launched a platform that pushes emojis and stickers from new brands into messaging apps. Brands pay for the privilege, as they would with a regular ad campaign.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Wang studied computer programming while growing up in China. After college, she hoped to move to the U.S. to start her career. The next year, the Chinese Students Protection Act was passed and Wang got her master's in computer science at University of Houston. She worked at several Silicon Valley startups (and launched her own, iBizWomen.com) until September 11, 2001. The attack inspired her to create Binary Group, a technology consulting company that works with the Federal Government. Over the past 16 years, Binary has helped its clients save piles of money -- like the Army 20th Support Command, which cut $60 million over five years for its satellite communication bandwidth requirements.
The Atlanta-based group expects sales, adjusted for acquisitions, divestitures and currency fluctuations, to rise 3 per cent, compared with its earlier forecast of between 4 per cent and 5 per cent.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

3) Tell Me More: “I’m all ears.” It’s the ultimate conversation starter! When you signal that you’re open and intrigued, the other party will respond in kind. And who can resist flattery? If your interest is genuine, you may just fuel a productive exchange.
披露表格还警告购汇者不得使用其他人的购汇额度。以前,灰色市场的货币兑换者经常把多个个人的购汇额度汇集起来,靠这种手段来获取大量外汇。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: 人才争夺战 抢得来更要留得住
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

10. Mail carrier

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

But retail sales growth softened to 10 per cent in October, betraying economists’ expectations it would hold steady at 10.7 per cent growth from September.
AMC频道的《广告狂人》(Mad Men)也是如此。该剧演到了第七季,剧中人物和20世纪60年代的背景似乎已被挖掘干净,不过它仍在让观众猜测结局,结局要到明年才播出。《黑道家族》(The Sopranos)结局模糊。《绝命毒师》(Breaking Bad)以沃尔特·怀特(Walter White)死去告终。现在,隐约显现的下一个电视谜题是唐·德雷珀(Don Draper)的最后时刻——究竟是死去还是活着。
[ni'glekt]
《美国队长3:内战》将于2016年5月6日在各大影院上映。美国队长与钢铁侠开战,你支持谁?

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

新晋的富翁包括第一位以戏剧制作人身份进入榜单的卡梅隆·麦金托什,WeWork的亚当·诺依曼和米格尔·麦凯尔维,以及图片分享网站Pinterest的创始人本·希伯尔曼和埃文·夏普。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 公积金月缴存额下月起上调
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

全国具有大学教育程度的人口达17093万人,每10万人中受过高等教育的人口已由2010年的8930人上升至2015年的12445人。此外,我国上过高中的人数也有所增长,而只完成低水平教育的人数则有所下降。
一部富有感染力的、描写一名年轻黑人男同性恋成长故事的影片《月光男孩》(Moonlight),获得2017年奥斯卡(Oscar)最佳影片奖。不过,该片险些与此奖项擦肩而过,原因是在混乱的颁奖现场,此奖项曾被误颁给了《爱乐之城》(La La Land)。
We have always adopted an open mind and approach to the various regional trading arrangements, and we will also welcome progress in these arrangements or proposed arrangements. China will continue to remain engaged and participate in the liberalization of global trade.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

我们就是要用政府的“痛”换来企业的“顺”,让企业轻装上阵,提高竞争力。
Making Airbnb go away might not be so easy. A recent Quinnipiac poll found that 56 percent of the responders thought New Yorkers should be allowed to rent rooms out to strangers. “We don’t want to turn into hotels, but at the same time people want to rent out their apartments sometimes,” said Paul R. Gottsegen, the president of Halstead Management Company, which manages 250 residential properties in the city.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

深入推进“互联网+”行动和国家大数据战略;
蒋依依说,2013年人民币兑美元汇率上涨近3%,使北京成为了一个更加昂贵的旅游目的地。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

但曼谷的吸引力也显而易见:充满生机、食物美味、毗邻一些世界上最美的海滩和岛屿。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: 安徽房地产开发投资突破5000亿元
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

最佳电影提名应该可以肯定。参演《至暗时刻》的加里?奥德曼是最佳男主角的最热人选,如果说有谁能击败他的话,那可能就是蒂莫西?柴勒梅德了。
corn
There were also shows that didn’t live up to early expectations but still had traction, most notably “The Affair,” on Showtime, which began as a Hamptons film noir and instead turned into a French art film. The crime may not be commensurate with the series’s punishingly slow pace and “Rashomon"-like storytelling, but the series picked up momentum — and suspense — in the final episodes.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

'A little bit in shock,' said director Steve McQueen, before shrugging 'Roll, Jordan, roll'-the lyrics to the old gospel song sung in the slavery epic.
201309/256019.shtml
刘非也是汉朝皇帝汉武帝(公元前141-97在位)的同父异母兄弟。
No matter what the inherent method of momentum, all of these engines leverage the latest engine technology to maximize both their power and fuel economy, and run the gamut from the tiny and efficient 1.0-liter turbocharged three-cylinder unit offered in the Ford Fiesta to the Chevrolet Corvette Stingray’s mammoth 6.2-liter V8 that proves there’s no substitute for sheer displacement. We’re featuring Wards’ 10 Best Engines in the accompanying slideshow.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

自从18个月前在亚洲设立业务以来,克拉布一直没有涉足香港房地产市场,因为他表示,价格太高了,可担负性太差。
orig升起,开始+in→[生命]开始→起源;出身+al→起源的;独创的

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

从什么时候起,冬季成了一年中电视节目最丰富的季节?今年秋天有许多首播电视剧做了有组织的盛大宣传,获得不少关注,但更多有趣的剧集还是在一年中的前三个月中登陆有线台、无线台和网络。
“即使你已经接受美联储加息的现实,也还有其他原因感到紧张,”美银美林(Bank of America Merrill Lynch)新兴市场负责人戴维樠纳(David Hauner)表示。他指出,油价不断下跌和中国经济增长放缓,是CBOE的VIX指数(反映投资者情绪的晴雨表)所衡量的市场波动水平自8月以来居高不下的其中两大原因。
谈到他想让他们的关系“正式化”的愿望,拉格菲尔德曾表示:“目前还没有人类和动物结婚的……我从未想过我会像这样爱上一只猫咪。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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但行业观察人士说,这样的观点忽略了一个中国在创新方面与西方竞争对手直接对峙的领域:让中国版本更具互动性、使用起来也更有趣的那些额外功能。
The Handmaid's Tale

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