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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

However, the competition in the finance industry was also fierce. Graduates were advised to start with entry-level jobs and constantly improve their comprehensive capabilities to stay competitive.
根据电影监管机构数据显示,中国电影票房销售额在去年同比了增长48.7%

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

At the center of the speculation is BlackBerry’s healthy intellectual property portfolio, 44,000 patents and still growing. Last October, for example, the company won at least 27 new ones—covering everything from conference-calling interfaces to touch screens to security features for wearable technologies such as smart watches, eyeglasses and fitness bands. Security continues to be BlackBerry’s biggest selling point with businesses. Just ask the Sony movie studio division, which “resorted” to outdated BlackBerrys to restart communications after its security breach last Thanksgiving.
不过,多个大城市新建住宅价格增速似乎已显著放缓。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

One suggested change: require rent-stabilized tenants to verify their income.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

源于:strike(v 打击;军事进攻;铸造;敲钟;罢工)

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

这个所谓的“百万富翁的游乐场”现已向所有人敞开怀抱。经济型的酒店、家庭旅馆以及带有自助厨房的公寓,都使得塞舌尔之行不再价格高昂。塞舌尔由100多个散布在印度洋上的岛屿组成,这里有多种多样的娱乐活动供您选择,诸如沙滩浴、钓鱼、潜水、航海和乘船游览。塞舌尔群岛一年四季的热带气候可谓得天独厚,所以你随时都可以开始你的塞舌尔之行。
“Why do we keep getting so many record-warm years?” Dr. Schmidt asked in an interview. “It’s because the planet is warming. The basic issue is the long-term trend, and it is not going away.”
墓地主人的身份依然是个迷。这座墓地曾经被盗过,而且墓地中没有任何的文字记录来表明这些死者的名字以及他们的职位。
她曾为Glitzy Girl、Sally Miller和Purple Pixies等服装公司担任模特,也为《Teen Vogue》《Cosmopolitan》《Elle》和《Seventeen》等杂志拍摄照片。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
From the themed collection: 北京站28分钟到通州
Perspective

Trends and targets in antiviral phototherapy

发型。略长的卷发——蛤?你不是自来卷哦?小可怜,那你只好每晚带着卷发夹入睡了。
White people’s officially privileged status waned over the latter half of the 20th century with the demise of discriminatory practices in, say, university admissions. But rising wages, an expanding social safety net and new educational opportunities helped offset that. Most white adults were wealthier and more successful than their parents, and confident that their children would do better still.
Before that, she starred in popular sitcom, and has also made a name for herself in films.
她笔下的人物们觉得自己为了登上“美国梦”的山巅,经历了漫长的排队等候,但是上山的队伍放慢了速度,甚至停顿下来了。而那些移民、黑人和其他“外来者”似乎还在插队。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

However the prolonged period of contraction fits with the overall pattern of the slowing Chinese economy.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 前2月一线土地出让增84%
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

这篇文章发表后,美国参议院很快投票通过了《反就业歧视法》(Employment Non-Discrimination Act)。这样,在工作中歧视LGBT群体也有可能成为违法行为。这项法案即将提交众议院审议。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

n. 谈话,演讲
美国时间上周日,乡村音乐界的大牌们齐聚拉斯维加斯,出席2013年乡村音乐学院奖颁奖典礼。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

交通运输部科学研究院近日发布的报告显示,北京位居全国十大最拥堵城市排行榜第三,排在济南、哈尔滨之后。
I'm pleased to see manufacturing jobs returning to the U.S., but I don't expect the manufacturing industry to have the galvanic effect on the economy that many hope for. Why? Because automation will sharply erode the number of jobs any factory requires. The disappearance of blue-collar and entry-level jobs is already a problem, and that problem will grow.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 陶瓷产业发展带出人才聚集效应
Open Access Review Article

Diagnostic technologies for COVID-19: a review

但最近,回购势头开始减弱。跟踪回购比例最大的100家公司的标准普尔500回购指数最近创下了自2012年年中以来的首次下跌。随着股价连创新高,股票回购所产生的推动作用消失,公司投资较长期项目或使用多余现金进行收购变得更有价值。
The Fed last month laid out a timetable to slow the pace of its bond purchases throughout the year. The central bank, which had been soaking up $85 billion a month in Treasurys and mortgage-backed securities since late 2012, plans to reduce the pace of purchases by $10 billion at each meeting until it is no longer buying bonds at year-end.

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: LED照明市场饱和 OLED开始发威
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

10. A bad marriage can lead to an early death
Ann Hand
n. 会议记录,(复数)分钟
伦敦商学院(LBS)连续三年蝉联欧洲商学院排行榜桂冠,但其在欧洲大陆的竞争对手在用于编制榜单的单项排名中领先。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

8. 亚马逊的自助出版工具

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

改编自上世纪70年代真实贿赂事件的影片《美国骗局》当晚表现更加抢眼,埃米?亚当斯(Amy Adams)和珍妮弗?劳伦斯(Jennifer Lawrence)凭此片分获最佳女主角和最佳女配角奖。《为奴十二年》虽在提名数量上与《美国骗局》打平,参与了七个奖项的角逐,但当晚只摘得最佳剧情片一个奖项。
China's manufacturing sector last month expanded at the slowest pace since March.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
From the themed collection: 京城建材“明星”闪耀河北工业园
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Are you heading to Rio for the Olympics? Will you leverage the Google Maps app on Android or iOS? I think you already have the answer.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
From the themed collection: 修法并不意味小产权房会转正
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

jar

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

在根据真实罪案改编的电影《狐狸猎手》(Foxcatcher)中,以出演喜剧闻名的演员史蒂夫·卡瑞尔(Steve Carell)饰演大富翁约翰·E·杜邦(John E. du Pont)时隐藏在假面具后面。这个造型最突出的就是鸟嘴状鼻子。
穆迪分析(Moody's Analytics)在报告发布之前表示:“由于大宗商品价格不断下跌,生产者价格仍将处于下行趋势。”
中国外汇储备出现史无前例的下跌,已经引发市场担心:如果资本外流持续下去,而央行继续捍卫汇率,外储可能迅速蒸发。多数分析师相信,中国央行将被迫缩减干预力度,以免外汇储备进一步枯竭。
7.狱警

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

If successful, Hurun estimates that Mr Wang’s net worth could soar past $50bn, making him one of the world’s 10 richest men.
在本届戛纳电影节上,女性电影制作人以及相关女性话题曾广受关注成为宣传主题。28年来,戛纳首次以女导演拍摄的电影拉开序幕,伊莎贝拉?罗西里尼(Isabella Rossellini)成为“一种关注”单元评审团主席,莎尔玛?海雅克(Salma Hayek)主持讨论会高调探讨女性角色在电影中的意义。可以讨论的话题有许多,但是真的有何改变吗?数字似乎更能说明问题,主竞赛单元的19部入围作品仅有2部来自女性导演。而后发生的“高跟鞋门”,更有.....面对外界对于影展涉嫌性别歧视的负面消息,艺术总监蒂埃里?弗雷莫(Thierry Frémaux)一点儿反应都没。他只是说,戛纳电影节的举办有着及其不公平的高标准,参展影片不能申请其他诸如威尼斯或柏林电影节。这难道是建议人们去“攻击奥斯卡”?
如今,蓬勃发展的互联网经济在支撑我国信息技术(IT)行业财富增长方面正发挥着越来越重要的作用。
2. 米拉?库妮丝
China, the world’s most populous country, ranks No. 20 overall. It is considered to be the third most powerful nation and the second best country in which to start a business.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

More than 90 per cent of alumni from the most recent graduating classes accepted a job offer within three months of completing their programme.
4.阿迪达斯。品牌喜爱度:35%/排名:25

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

单词charity 联想记忆:

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

去年2月份中国国家旅游局启用一个名为“美丽中国”的标志,意在向海外宣传推广其旅游形象,然而有人讽刺“美丽中国”这一名称与中国城市在严重污染之下那一张张“不太美丽”的照片相比反差太大。希望专家们今后能设计出一个好一点的方案来。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

[.?ndi'nai?bl]
就毕业3年后的学员薪资而言,德国的管理硕士课程排名居前,有3所商学院进入前4名。奥托贝森管理研究院(WHU Beisheim)的毕业生享有薪酬最高的名声,平均薪资为9.8123万美元。
工业企业利润由上年下降2.3%转为增长8.5%;
该片是《X战警:未来昔日》的续集,也是《X战警》系列电影的最新力作。我们将在片中看到“X战警”大战恶棍“天启”(Apocalypse)。很多昔日的面孔将回归,当然也会有不少新角色出现。 关于电影,我们知道的也仅此而已了,但可以保证的是,这绝对是一部超赞的电影。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

mass
Here is a silver lining: Market-rate rents are so high that they probably will not climb much higher next year. “The good news is rents aren’t rising anymore,” Mr. Miller said. “The bad news is they are probably not going to fall.”
China's Ministry of Education (MOE) said at a news conference that most of the world's foreign students who study abroad are from China.
'While RMB is on the rise, currencies from some of China's competitors for tourism, such as Japan, are depreciating, meaning travel to some other Asian countries has been getting cheaper while travel to China is becoming more costly,' Jiang Yiyi said.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

远离熙熙攘攘的繁华都市,密歇根上半岛主打自然风景与美景,种种景观令人叹为观止。
推进国际贸易和投资自由化便利化。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Experts say that 2016 was a remarkable year for the Chinese film industry as it realized growth while facing multiple challenges including the rapid development of the internet, the increasingly sophisticated tastes of Chinese audiences, and the economic downturn in the country.
2014年、2015年的研发经费增速分别为9.9%和8.9%。研发经费在去年国内生产总值(GDP)中的占比为2.11%,比上年提高0.05个百分点。
10) You’re Right: Want to get someone’s attention? Tell him that he’s right. Once you yield the high ground, it’s much easier for the other party to swallow that the right plan and sentiment can’t always overcome the absurdities and restraints we face every day.
这支队伍需要更多的天赋,他们需要大修。对魔术而言,最能吸引天赋到来的方式一直以来都是选秀。
“Through the second half of the 20th century we had this big dispersion of trade and economic activity around the world. All this specialisation meant exports rose faster than GDP,” Mr Williams says.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

与此同时,大学毕业生选择继续深造的意向也降低了,这让今年选择就业的人数比例达到了75.6%,而去年这一数据为71.2%。
The dollar value of outbound shipments from China rose 12.3 per cent year on year in November, lifting from a revised pace of 6.8 per cent in October, and smashing a median forecast of 5 per cent from economists polled by Reuters.
9. The Chinese militarywill demand and receive vastly expanded investments in the form of advancedaircraft and ships.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

在所有这些影片中,斯文顿用的是同一个牙齿设计专家——伦敦Fangs F/X公司的克里斯·莱昂斯(Chris Lyons)。他在工作中设计了各种牙齿,包括为坎耶·韦斯特(Kanye West)一个音乐录影带中的一只杜宾犬设计了金色尖牙。
肥皂剧通常都在电视收视排行榜上位居前列,但2012最流行的电视节目是英国广播电台儿童节目《麦克小骑士》,它打败了美国惊悚电视剧《国土安全》和真人秀节目《Towie》。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

单词coach 联想记忆:
统计数据显示,在2009年之前,全球研发支出以每年约7%的速度增长,但在2014年放缓了4%。
“Even though there is significant awareness [of the role of Fed policy], market dynamics can become unstable or unfavourable relatively easily,” he says. “Then you get into a self-reinforcing cycle of selling pressure.”

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

赢家:雷霆
四年前,玛蒂还是一个默默无闻的8岁小女孩,她喜欢跳舞,就读于当地一所小学。
Common 和 Day 将会演绎电影《马歇尔》中的歌曲《Stand Up For Something》还有Settle会演唱电影《马戏之王》中的歌曲《Thisis me》。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

会计和咨询业

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
From the themed collection: 上半年房地产市场迎来小高潮
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

1983年的夏天,早熟的17岁少年埃利奥与家人一同在意大利北部伦巴第的17世纪乡间别墅度假。他邂逅了英俊的博士生奥利弗,后者是埃利奥父亲的实习生。那个夏天,一切都沉醉在灿烂阳光中,埃利奥和奥利弗彼此探索着欲望觉醒带来的令人晕眩的美。这个夏天将改变他们的一生。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

“It suggests that people put more weight on what happened to themselves and less weight on other information that might be available,”Koudijs says. The more personally removed people are from an important event, the less it is to affect their appetite for risk.
This year has been one of diverse and bold hair and makeup choices, from the frizzy, matted blue-tinted mane of the Witch in “Into the Woods” to the shimmering, expertly shaped pompadour of James Brown in “Get On Up.” In some cases, the absence of hair comes into play, like the bald, heavy-on-the-eyeliner look of Ramses in “Exodus: Gods and Kings.”

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

The second chart shows the real federal funds rate (ie discounting for inflation) and the real natural rate. Again, when the federal funds rate is above its natural rate, EM crises are more common.
“授课的是一流从业者,”该学院一名毕业生表示,“该项目为只有极少金融业工作经验的年轻专业人士量身打造,学生们毕业后马上就能投入工作。”
下面是开发一个商业平台时需要考虑的主要元素。这些元素可以帮助任何新公司制定明智的策略:
A cheery New Year hold lots of happiness for you!给你特别的祝福,愿新年带给你无边的幸福、如意。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

Columbia Pictures克里斯蒂安?贝尔、艾米?亚当斯和布莱德利?库珀在电影《美国骗局》中早在1月份闹片荒的时候,人们不会想到今年会迎来如此多好电影。不仅如此,有几部影片甚至达到了被我们在心目中理想化了的那些老电影的水准。今年有两部电影脱颍而出。纯娱乐片方面,赢家显然是《美国骗局》(American Hustle),这部由大卫?欧?拉塞尔(David O. Russell)执导的影片讲述了上个世纪七十年代的行骗高手和他们的微妙骗术的故事,幽默诙谐,令人捧腹。而从创新角度看,《地心引力》(Gravity)的全新拍摄技术给观众带来了新的观影体验。人们普遍认为《美国骗局》无可挑剔,这部疯狂喜剧片是一部时代佳作。我个人则认为,《地心引力》是今年的最佳影片。
不过另一个因素也影响着最新一集《007》的计划,主演“詹姆斯-邦德”丹尼尔-克雷格全心投入于演出《千禧年三部曲》,而其中的《龙文身的女孩》正在紧张拍摄中。而目前电影公司也没有遴选新一任007的打算,若果丹尼尔三度出演这一角色,电影至少得等到2014年才能上映。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 家居电商无可回避 O2O面临尴尬
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

We also do not want any trade war with others and we have stuck to reform of the yuan's exchange rate formation mechanism to keep it basically stable at reasonable and equilibrium levels.
年龄:46

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

The dollar value of China’s exports and imports grew in November after two months of contraction and in the face of a rally by the greenback that followed last month’s US presidential election.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
From the themed collection: 那些做大家居的企业还好吗?
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

Succeeding as an entrepreneur takes hard work and persistence because, unfortunately, there is no business-startup fairy who magically bestows success on small businesses and their owners.
Against: It might be that bit too far from the mainstream to make a huge awards impact.
总的来说,在选择就读EMBA的原因中,创业排在最末(10分中得5.5分)。学员的主要动机是学习管理(9.1分)、拓宽人脉(8.3分)及增加收入(8.1分)。
如何找到IP地址

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

5.Emma Watson
项目总成本:9.8906万美元

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

The Beijing Tourism Development Commission noted that the country's battle with pollution is another obstacle cities face in attracting inbound tourists.
Bond King Bill Gross admits, 'QE must end.' Trillions of cheap money 'has distorted incentives and inflated asset prices to artificial levels.' But now Gross says 'the Fed plan may be too hasty.'
1983年的夏天,早熟的17岁少年埃利奥与家人一同在意大利北部伦巴第的17世纪乡间别墅度假。他邂逅了英俊的博士生奥利弗,后者是埃利奥父亲的实习生。那个夏天,一切都沉醉在灿烂阳光中,埃利奥和奥利弗彼此探索着欲望觉醒带来的令人晕眩的美。这个夏天将改变他们的一生。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
From the themed collection: 建筑垃圾重生 循环利用成建材
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

n. 回想,记忆,纪念品
Warm greetings and best wishes for happiness and good luck in the coming year.衷心祝福来年快乐、幸运!
2010年最让人痴迷的东西是备受期待的iPhone,其他受关注的对象还有女演员林赛 罗韩、iPad、电视节目《欢乐合唱团》和《泽西海岸》。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

前“以色列小姐”盖尔·加朵在2015全球十大美女榜中居第六位。她是服装品牌“卡斯特罗”的首席模特。加朵因饰演《速度与激情》系列电影里的吉泽尔· 姬赛儿一角而闻名于世。
The Amsterdam crisis began when a Dutch group known as the Seppenwolde syndicate made a big, contrarian bet on the shares of East India Company. Those shares had plunged in 1771 mainly because of losses in Bengal, but the company kept paying high dividends and covered up its shortfalls by borrowing money. Convinced that East India shares would quickly rebound, the Seppenwolde group aggressively bought them on margin. But instead of rebounding, the shares fell even further after the company slashed its dividend.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

strictly
献上节日的问候与祝福,愿你拥有一个充满生机和欢乐的新年。
“这是真的“我必须去做这件事”的时刻了,”他说。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

2014年、2015年的研发经费增速分别为9.9%和8.9%。研发经费在去年国内生产总值(GDP)中的占比为2.11%,比上年提高0.05个百分点。
That was true, too, of “Mad Men” on AMC. which in its seventh season has all but exhausted its characters and its 1960s setting, but is still keeping viewers guessing about the end, which won’t air until next year. “The Sopranos” ended ambiguously. “Breaking Bad,” put an end to Walter White. Now, the next television mystery looming ahead centers on Don Draper’s last moments, dead or alive.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

基地方面希望借此提升公众意识,宣扬保护区及熊猫保护的理念,同时在中国进行动物野生放归,增加中国部分物种濒危区的动物数量。
在简历中提到你的孩子和嗜好没有任何好处。永远不要说,“我的孩子上大学了,我就能安心回到工作岗位了。”
It was visible in practically every brand that edged from the 1960s to 1970s for the season currently in stores, including Alberta Ferretti, Pucci and Etro.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

我认为这篇文章是上篇文章“成为一个足球寡妇”的完美续篇,在这篇文章里面我分享了八大规则,其中我觉得第六条最重要。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

2017年排行榜分别评选了60个“无工作经验要求”的项目和6个“有工作经验要求”的项目。“无工作经验要求”的项目主要面向拥有很少或没有金融业背景的学生,“有工作经验要求”的项目针对的是已经在金融领域工作的专业人士。只有少数几家学院提供“有工作经验要求”的课程。
In Pakistani Fray, Maryam Sharif Is on the Edge of Power, or Prison

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

6月28日
But now she's using her storybook looks for good, dressing up as the character to entertain children and cheer-up cancer patients.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

“我……学会了与来自其他文化及社会的人们进行互动,”一位来自瑞典的毕业生说。
下载微信之后,用户会收到提示,让他们用自己的QQ账号或手机号注册。随后微信利用用户手机通讯录里已有的条目来充实联络人列表。进行交流时,用户可以上传任何照片或视频到手机上,也可以拍摄新的照片和视频,或是按下一个按钮录制一条语音信息,信息的传送几乎是实时的。语音信息可以回放,信息最后有短暂的哔声,模仿无线电对讲机那种即时联络的感觉。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

让别人都滚粗闭嘴,这样你就能特别牛掰地走入“记忆宫殿”了。
But even in a bad economy some jobs are just not worth it. Are there any telltale signs you should be looking for when trying to decide if you throw in the towel? Here are ten signs to look for to determine if it's time to find a new job:

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

4. We can’t go into detail on this matter.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

The general weakness in the renminbi, which fell 1.3 per cent in January and had weakened by 2.2 per cent in the final quarter of 2015, is likely playing a part, by making overseas goods more expensive. However, exports have yet to receive a boost from the currency’s depreciation.
读:游艇
Floodwaters surround homes near the Mantoloking Bridge the morning after Sandy hit Mantoloking, New Jersey.
In the US, New York, California and Texas received the most investment. Chinese firms invested $5.4bn in New York, the top beneficiary, with most of the money spent on three big financial services and real estate deals.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Employees of state-owned firms also expressed more satisfaction with their bonuses than those at private companies – and little wonder, as the average payout at the former was Rmb17,318, or about Rmb6,000 more than what their private-sector counterparts could expect.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

土耳其外交部愤怒地驳斥了欧盟的批评。它说:“欧盟应该意识到,这种声明助长了极端主义,比如仇外和反土耳其情绪,因为它对避免过分言论和行动以免局势进一步恶化的呼吁,针对的只是土耳其,而不是所有违反外交公约和国际法、从而导致了这种局面的国家。”
E.E.卡明斯有句话说得很有道理,“除了你自己,不要成为任何人,在这个竭尽全力、不分日夜想把你变成别人的世界里,这样做意味着迎接人类最艰苦的战斗;永不停息,战斗到底。”
人社部下属的社会保障研究所的所长金维刚称,鉴于居民消费价格指数低于预期、工资和GDP涨幅也有所放缓,所以今年上调5.5%这一数字是合理的。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
From the themed collection: 2016年卫浴洁具十大品牌排行榜
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

如果一个“推文幼稚的像个幼儿园小朋友”一样最年长的人,都可以当选总统,那为什么反过来不试一下,看看年轻人能否当选并明智地执政?
户外空间:这栋房屋占地面积五分之一英亩(约809平方米)由纽约公司Landgarden负责景观设计。房屋前面的这座日式花园中采用了当地的植物。这栋房屋后面还有一处露台和院子,那里还有一座日式花园。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
From the themed collection: 北京:广内地下空间变身便民仓储
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

?Bond has it all and that's exactly what the most beautiful women demand in the men they date. Women who really enjoy sex prefer "bad boys" -- and there's no doubt 007 qualifies. Feminine women prefer masculine men. And for one night stands women look for physical attractiveness and dominance -- which Bond has in spades.
Variety Talk Series: “Last Week Tonight With John Oliver” (HBO)

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
From the themed collection: O2O将会是板材行业的翻身机会吗?
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

China does not want to see a trade war between the US and China. That would not make our trade fairer and cause loss for the both sides.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

他做了几次化妆试验,希望能极大改变卡瑞尔的外貌。“我们实际上在创造一个新人,”科森说。
She said: 'On a scale of one to 10, I feel I'm at a nine because there's definitely room for improvement. I know I could go further.'
国际机器人联合会主席Junji Tsuda在他的《全球工业机器人市场》报告中指出,在2017年,全球约有38.7万台工业机器人售出,同比增长31%,创造了500亿美元的收入,而中国则是这一强劲增长背后的关键驱动因素之一。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
From the themed collection: 家居卖场闭市 谁为风险埋单?
Paper

Length-scale dependence of protein hydration-shell density

“写这本书的一大挑战是异性恋男人能改变一个女人的生活并使她死心塌地的看法。”
stroke
这是2015年1月11日发布在伊斯兰主义社交网站上的视频截图,显示了一个自称为AmedyCoulibaly的男人,声称就是他在2015年1月9日杀死了犹太超市的四个人质。
Do your homework. Read the assigned pages, and then some. Plug your topic into the Internet, grab another book at the library, and see what else you can learn about the subject.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

demo人民+-ic…的→民主的,民主主义的;民主政体的
One of the main strengths of the LBS programmes is the wide range of students from different countries. More than 90 per cent in its 2015 MBA cohort were from overseas, coming from about 60 different countries.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

我不了解你是什么样的情况,但是如果我根据工作,生活和生活各自准备一个日历,我会手忙脚乱的。如果你生活中所有的事都记在一个日历上,在一个计划中,你就不能重复安排任何事了,就像一个重要的测试或者和老板的晚餐一样。
立场:呼吁进行移民改革
n. 全体船员,全体乘务员,(一组)工作人员

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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About this collection

中国的旅游业官员正力图在2014年扭转入境游客减少的情况,专家认为,如果能对其过时的旅行团进行改进并降低票价,这一计划就有可能实现。
British statisticians’ unwillingness to correct known errors in the clothing price component of the RPI redistributes many billions every year from students, recent graduates, taxpayers and rail commuters to index-linked UK government bondholders, wealthy pensioners with RPI-linked pensions and rail companies.

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